An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells.

Susceptibility to the human autoimmune disease insulin-dependent diabetes mellitus is strongly associated with particular haplotypes of the major histocompatibility complex (MHC). Similarly, in a spontaneous animal model of this disease, the nonobese diabetic (NOD) mouse, the genes of the MHC play a...

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Bibliographic Details
Main Authors: Singer, S M, Tisch, R, Yang, X D, McDevitt, H O
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC47610/
https://ncbi.nlm.nih.gov/pubmed/8415742
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