Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression

Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme degradation, is a cytoprotective enzyme upregulated in the vasculature by increased flow and inflammatory stimuli. Human genetic data suggest that a diminished HO-1 expression may predispose one to abdominal aortic aneurysm (AAA) development....

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Azuma, Junya, Wong, Ronald J., Morisawa, Takeshi, Hsu, Mark, Maegdefessel, Lars, Zhao, Hui, Kalish, Flora, Kayama, Yosuke, Wallenstein, Matthew B., Deng, Alicia C., Spin, Joshua M., Stevenson, David K., Dalman, Ronald L., Tsao, Philip S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760983/
https://ncbi.nlm.nih.gov/pubmed/26894432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149288
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