Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression

Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme degradation, is a cytoprotective enzyme upregulated in the vasculature by increased flow and inflammatory stimuli. Human genetic data suggest that a diminished HO-1 expression may predispose one to abdominal aortic aneurysm (AAA) development....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Azuma, Junya, Wong, Ronald J., Morisawa, Takeshi, Hsu, Mark, Maegdefessel, Lars, Zhao, Hui, Kalish, Flora, Kayama, Yosuke, Wallenstein, Matthew B., Deng, Alicia C., Spin, Joshua M., Stevenson, David K., Dalman, Ronald L., Tsao, Philip S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760983/
https://ncbi.nlm.nih.gov/pubmed/26894432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149288
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