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Isoflurane, But Not the Nonimmobilizers F6 and F8, Inhibits Rat Spinal Cord Motor Neuron Ca(V)1 Calcium Currents

BACKGROUND: Volatile anesthetics decrease Ca(2+) entry through voltage-dependent Ca(2+) channels. Ca(2+) influences neurotransmitter release and neuronal excitability. Because volatile anesthetics act specifically on the spinal cord to produce immobility, we examined the effect of isoflurane and the...

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Publicado en:Anesth Analg
Main Authors: Recio-Pinto, Esperanza, Montoya-Gacharna, Jose V., Xu, Fang, Blanck, Thomas J.J.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760920/
https://ncbi.nlm.nih.gov/pubmed/26702867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000001111
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