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Isoflurane Inhibits CREB Phosphorylation and Calmodulin Translocation to the Nucleus of SH-SY5Y Cells
BACKGROUND: Calmodulin activation by Ca(2+), its translocation to the nucleus, and stimulation of phosphorylation of CREB (P-CREB) is necessary for new gene expression and has been linked to long term potentiation, a process important in memory formation. Since isoflurane is known to affect memory w...
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| Publicado no: | Anesth Analg |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4503314/ https://ncbi.nlm.nih.gov/pubmed/19762740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3181b5a1b8 |
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