IL-21 and Probiotic Therapy Improve T(H)17 Frequencies, Microbial Translocation, and Microbiome in ARV-Treated, SIV-Infected Macaques

Increased mortality in antiretroviral (ARV)-treated, HIV-infected individuals has been attributed to persistent immune dysfunction, in part due to abnormalities at the gastrointestinal barrier. In particular, the poor reconstitution of gastrointestinal T(H)17 cells correlates with residual transloca...

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Библиографические подробности
Опубликовано в: :Mucosal Immunol
Главные авторы: Ortiz, Alexandra M., Klase, Zachary A., DiNapoli, Sarah R., Vujkovic-Cvijin, Ivan, Carmack, Kirby, Perkins, Molly R., Calantone, Nina, Vinton, Carol L., Riddick, Nadeene E., Gallagher, John, Klatt, Nichole R., McCune, Joseph M., Estes, Jacob D., Paiardini, Mirko, Brenchley, Jason M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760912/
https://ncbi.nlm.nih.gov/pubmed/26286233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.75
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