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IL-21 and Probiotic Therapy Improve T(H)17 Frequencies, Microbial Translocation, and Microbiome in ARV-Treated, SIV-Infected Macaques

Increased mortality in antiretroviral (ARV)-treated, HIV-infected individuals has been attributed to persistent immune dysfunction, in part due to abnormalities at the gastrointestinal barrier. In particular, the poor reconstitution of gastrointestinal T(H)17 cells correlates with residual transloca...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Ortiz, Alexandra M., Klase, Zachary A., DiNapoli, Sarah R., Vujkovic-Cvijin, Ivan, Carmack, Kirby, Perkins, Molly R., Calantone, Nina, Vinton, Carol L., Riddick, Nadeene E., Gallagher, John, Klatt, Nichole R., McCune, Joseph M., Estes, Jacob D., Paiardini, Mirko, Brenchley, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760912/
https://ncbi.nlm.nih.gov/pubmed/26286233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.75
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