Treatment of Mycobacterium tuberculosis-Infected Macrophages with Poly(Lactic-Co-Glycolic Acid) Microparticles Drives NFκB and Autophagy Dependent Bacillary Killing

The emergence of multiple-drug-resistant tuberculosis (MDR-TB) has pushed our available repertoire of anti-TB therapies to the limit of effectiveness. This has increased the urgency to develop novel treatment modalities, and inhalable microparticle (MP) formulations are a promising option to target...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lawlor, Ciaran, O’Connor, Gemma, O’Leary, Seonadh, Gallagher, Paul J., Cryan, Sally-Ann, Keane, Joseph, O’Sullivan, Mary P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760758/
https://ncbi.nlm.nih.gov/pubmed/26894562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149167
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