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Treatment of Mycobacterium tuberculosis-Infected Macrophages with Poly(Lactic-Co-Glycolic Acid) Microparticles Drives NFκB and Autophagy Dependent Bacillary Killing

The emergence of multiple-drug-resistant tuberculosis (MDR-TB) has pushed our available repertoire of anti-TB therapies to the limit of effectiveness. This has increased the urgency to develop novel treatment modalities, and inhalable microparticle (MP) formulations are a promising option to target...

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محفوظ في:

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	PLoS One
المؤلفون الرئيسيون:	Lawlor, Ciaran, O’Connor, Gemma, O’Leary, Seonadh, Gallagher, Paul J., Cryan, Sally-Ann, Keane, Joseph, O’Sullivan, Mary P.
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Public Library of Science 2016
الموضوعات:	Research Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4760758/ https://ncbi.nlm.nih.gov/pubmed/26894562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149167
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Treatment of Mycobacterium tuberculosis-Infected Macrophages with Poly(Lactic-Co-Glycolic Acid) Microparticles Drives NFκB and Autophagy Dependent Bacillary Killing

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