Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

Taxol inhibited HeLa cell proliferation by inducing a sustained mitotic block at the metaphase/anaphase boundary. Half-maximal inhibition of cell proliferation occurred at 8 nM taxol, and mitosis was half-maximally blocked at 8 nM taxol. Inhibition of mitosis was associated with formation of an inco...

Celý popis

Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Jordan, M A, Toso, R J, Thrower, D, Wilson, L
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8105478/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.20.9552
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!