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Ret and Etv4 Promote Directed Movements of Progenitor Cells during Renal Branching Morphogenesis

Branching morphogenesis of the epithelial ureteric bud forms the renal collecting duct system and is critical for normal nephron number, while low nephron number is implicated in hypertension and renal disease. Ureteric bud growth and branching requires GDNF signaling from the surrounding mesenchyme...

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Bibliografiska uppgifter
I publikationen:PLoS Biol
Huvudupphovsmän: Riccio, Paul, Cebrian, Cristina, Zong, Hui, Hippenmeyer, Simon, Costantini, Frank
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760680/
https://ncbi.nlm.nih.gov/pubmed/26894589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002382
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