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Hypoxia reduces placental mTOR activation in a hypoxia‐induced model of intrauterine growth restriction (IUGR)

Mammalian target of rapamycin (mTOR) is a protein that regulates cell growth in response to altered nutrient and growth factor availability. Our objective was to assess activated mTOR and its intracellular intermediates p70, and 4EBP1 in placental and invasive trophoblast cells in a hypoxia‐induced...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Kimball, Rebecca, Wayment, Montana, Merrill, Daniel, Wahlquist, Tyler, Reynolds, Paul R., Arroyo, Juan A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760431/
https://ncbi.nlm.nih.gov/pubmed/26660559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12651
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