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Placental mTOR and related signaling pathways in an Ovine Model of Intrauterine Growth Restriction (IUGR)

OBJECTIVE: Both phosphorylated (p) mTOR and p70(S6K) are known to regulate protein synthesis and are affected during intrauterine growth restriction (IUGR). We studied the mTOR pathway during hyperthermia (HT) induced IUGR in the sheep. STUDY DESIGN: Beginning at 40 dGA, four ewes were exposed to HT...

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Autori principali: Arroyo, Juan A., Brown, Laura D., Galan, Henry L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789863/
https://ncbi.nlm.nih.gov/pubmed/19800600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2009.07.031
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