Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases

The immune microenvironment of the brain differs from that of other organs and the role of tumor-infiltrating lymphocytes (TILs) in brain metastases (BM), one of the most common and devastating complication of cancer, is unclear. We investigated TIL subsets and their prognostic impact in 116 BM spec...

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Publicado en:Oncoimmunology
Autores principales: Berghoff, Anna S, Fuchs, Elisabeth, Ricken, Gerda, Mlecnik, Bernhard, Bindea, Gabriela, Spanberger, Thomas, Hackl, Monika, Widhalm, Georg, Dieckmann, Karin, Prayer, Daniela, Bilocq, Amelie, Heinzl, Harald, Zielinski, Christoph, Bartsch, Rupert, Birner, Peter, Galon, Jerome, Preusser, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760339/
https://ncbi.nlm.nih.gov/pubmed/26942067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1057388
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