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Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases

The immune microenvironment of the brain differs from that of other organs and the role of tumor-infiltrating lymphocytes (TILs) in brain metastases (BM), one of the most common and devastating complication of cancer, is unclear. We investigated TIL subsets and their prognostic impact in 116 BM spec...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Berghoff, Anna S, Fuchs, Elisabeth, Ricken, Gerda, Mlecnik, Bernhard, Bindea, Gabriela, Spanberger, Thomas, Hackl, Monika, Widhalm, Georg, Dieckmann, Karin, Prayer, Daniela, Bilocq, Amelie, Heinzl, Harald, Zielinski, Christoph, Bartsch, Rupert, Birner, Peter, Galon, Jerome, Preusser, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760339/
https://ncbi.nlm.nih.gov/pubmed/26942067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1057388
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