Long-lasting multifunctional CD8(+) T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination

Cytotoxic T cells are considered crucial for antitumor immunity and their induction is the aim of various immunotherapeutic strategies. High frequencies of tumor-specific CD8(+) T cells alone, however, are no guarantee for long-term tumor control. Here, we analyzed the functionality of tumor-specifi...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Wimmers, Florian, Aarntzen, Erik H. J. G., Duiveman-deBoer, Tjitske, Figdor, Carl G., Jacobs, Joannes F. M., Tel, Jurjen, de Vries, I. Jolanda M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760336/
https://ncbi.nlm.nih.gov/pubmed/26942087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1067745
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