Identification of RNF168 as a PML nuclear body regulator

Promyelocytic leukemia (PML) protein forms the basis of PML nuclear bodies (PML NBs), which control many important processes. We have screened an shRNA library targeting ubiquitin pathway proteins for effects on PML NBs, and identified RNF8 and RNF168 DNA-damage response proteins as negative regulat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Sci
Main Authors: Shire, Kathy, Wong, Andrew I., Tatham, Michael H., Anderson, Oliver F., Ripsman, David, Gulstene, Stephanie, Moffat, Jason, Hay, Ronald T., Frappier, Lori
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760303/
https://ncbi.nlm.nih.gov/pubmed/26675234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.176446
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