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Activation of the IGF1 pathway mediates changes in cellular contractility and motility in single-suture craniosynostosis
Insulin growth factor 1 (IGF1) is a major anabolic signal that is essential during skeletal development, cellular adhesion and migration. Recent transcriptomic studies have shown that there is an upregulation in IGF1 expression in calvarial osteoblasts derived from patients with single-suture cranio...
Zapisane w:
| Wydane w: | J Cell Sci |
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| Główni autorzy: | , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Company of Biologists Ltd
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4760302/ https://ncbi.nlm.nih.gov/pubmed/26659664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175976 |
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