Activation of the IGF1 pathway mediates changes in cellular contractility and motility in single-suture craniosynostosis

Insulin growth factor 1 (IGF1) is a major anabolic signal that is essential during skeletal development, cellular adhesion and migration. Recent transcriptomic studies have shown that there is an upregulation in IGF1 expression in calvarial osteoblasts derived from patients with single-suture cranio...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Al-Rekabi, Zeinab, Wheeler, Marsha M., Leonard, Andrea, Fura, Adriane M., Juhlin, Ilsa, Frazar, Christopher, Smith, Joshua D., Park, Sarah S., Gustafson, Jennifer A., Clarke, Christine M., Cunningham, Michael L., Sniadecki, Nathan J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760302/
https://ncbi.nlm.nih.gov/pubmed/26659664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175976
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