Effective combination treatment of GD2-expressing neuroblastoma and Ewing's sarcoma using anti-GD2 ch14.18/CHO antibody with Vγ9Vδ2+ γδT cells

Gamma delta T lymphocytes (γδT cells) have pleiotropic properties including innate cytotoxicity, which make them attractive effectors for cancer immunotherapy. Combination treatment with zoledronic acid and IL-2 can activate and expand the most common subset of blood γδT, which express the Vγ9Vδ2 T...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Fisher, Jonathan P H, Flutter, Barry, Wesemann, Florian, Frosch, Jennifer, Rossig, Claudia, Gustafsson, Kenth, Anderson, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760299/
https://ncbi.nlm.nih.gov/pubmed/26942051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1025194
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