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Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly

Biogenesis of the 12-subunit RNA polymerase II (Pol II) transcription complex requires so-called GPN-loop GTPases, but the function of these enzymes is unknown. Here we report the first crystal structure of a eukaryotic GPN-loop GTPase, the Saccharomyces cerevisiae enzyme Npa3 (a homolog of human GP...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Niesser, Jürgen, Wagner, Felix R., Kostrewa, Dirk, Mühlbacher, Wolfgang, Cramer, Patrick
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760217/
https://ncbi.nlm.nih.gov/pubmed/26711263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01009-15
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