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Glycogen Synthase Kinase 3β Is Positively Regulated by Protein Kinase Cζ-Mediated Phosphorylation Induced by Wnt Agonists

The molecular events that drive Wnt-induced regulation of glycogen synthase kinase 3β (GSK-3β) activity are poorly defined. In this study, we found that protein kinase Cζ (PKCζ) and GSK-3β interact mainly in colon cancer cells. Wnt stimulation induced a rapid GSK-3β redistribution from the cytoplasm...

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Publicado en:Mol Cell Biol
Main Authors: Tejeda-Muñoz, Nydia, González-Aguilar, Héctor, Santoyo-Ramos, Paula, Castañeda-Patlán, M. Cristina, Robles-Flores, Martha
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760212/
https://ncbi.nlm.nih.gov/pubmed/26711256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00828-15
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