Protein Kinase C Delta Negatively Modulates Canonical Wnt Pathway and Cell Proliferation in Colon Tumor Cell Lines

The tumor suppressor Adenomatous Polyposis coli (APC) gene is mutated or lost in most colon cancers. Alterations in Protein kinase C (PKC) isozyme expression and aberrant regulation also comprise early events in intestinal carcinomas. Here we show that PKCδ expression levels are decreased in colon t...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Hernández-Maqueda, José G., Luna-Ulloa, Luis Bernardo, Santoyo-Ramos, Paula, Castañeda-Patlán, M. Cristina, Robles-Flores, Martha
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592802/
https://ncbi.nlm.nih.gov/pubmed/23520519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058540
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