Icariin displays anticancer activity against human esophageal cancer cells via regulating endoplasmic reticulum stress-mediated apoptotic signaling

In this study, we investigated the antitumor activity of icariin (ICA) in human esophageal squamous cell carcinoma (ESCC) in vitro and in vivo and explored the role of endoplasmic reticulum stress (ERS) signaling in this activity. ICA treatment resulted in a dose- and time-dependent decrease in the...

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Pubblicato in:Sci Rep
Autori principali: Fan, Chongxi, Yang, Yang, Liu, Yong, Jiang, Shuai, Di, Shouyin, Hu, Wei, Ma, Zhiqiang, Li, Tian, Zhu, Yifang, Xin, Zhenlong, Wu, Guiling, Han, Jing, Li, Xiaofei, Yan, Xiaolong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759694/
https://ncbi.nlm.nih.gov/pubmed/26892033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21145
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