Icariin displays anticancer activity against human esophageal cancer cells via regulating endoplasmic reticulum stress-mediated apoptotic signaling

In this study, we investigated the antitumor activity of icariin (ICA) in human esophageal squamous cell carcinoma (ESCC) in vitro and in vivo and explored the role of endoplasmic reticulum stress (ERS) signaling in this activity. ICA treatment resulted in a dose- and time-dependent decrease in the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fan, Chongxi, Yang, Yang, Liu, Yong, Jiang, Shuai, Di, Shouyin, Hu, Wei, Ma, Zhiqiang, Li, Tian, Zhu, Yifang, Xin, Zhenlong, Wu, Guiling, Han, Jing, Li, Xiaofei, Yan, Xiaolong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759694/
https://ncbi.nlm.nih.gov/pubmed/26892033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21145
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