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Plasma radiometabolite correction in dynamic PET studies: Insights on the available modeling approaches

Full kinetic modeling of dynamic PET images requires the measurement of radioligand concentrations in the arterial plasma. The unchanged parent radioligand must, however, be separated from its radiometabolites by chromatographic methods. Thus, only few samples can usually be analyzed and the resulti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Tonietto, Matteo, Rizzo, Gaia, Veronese, Mattia, Fujita, Masahiro, Zoghbi, Sami S, Zanotti-Fregonara, Paolo, Bertoldo, Alessandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759680/
https://ncbi.nlm.nih.gov/pubmed/26661202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X15610585
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