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Measuring specific receptor binding of a PET radioligand in human brain without pharmacological blockade: The genomic plot

PET studies allow in vivo imaging of the density of brain receptor species. The PET signal, however, is the sum of the fraction of radioligand that is specifically bound to the target receptor and the non-displaceable fraction (i.e. the non-specifically bound radioligand plus the free ligand in tiss...

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Detalhes bibliográficos
Publicado no:Neuroimage
Main Authors: Veronese, Mattia, Zanotti-Fregonara, Paolo, Rizzo, Gaia, Bertoldo, Alessandra, Innis, Robert B., Turkheimer, Federico E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983715/
https://ncbi.nlm.nih.gov/pubmed/26850512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2016.01.058
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