A novel quantitative high-throughput screen identifies drugs that both activate SUMO conjugation via the inhibition of microRNAs 182 and 183 and facilitate neuroprotection in a model of oxygen and glucose deprivation

The conjugation/de-conjugation of Small Ubiquitin-like Modifier (SUMO) has been shown to be associated with a diverse set of physiologic/pathologic conditions. The clinical significance and ostensible therapeutic utility offered via the selective control of the global SUMOylation process has become...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Cereb Blood Flow Metab
Main Authors: Bernstock, Joshua D, Lee, Yang-ja, Peruzzotti-Jametti, Luca, Southall, Noel, Johnson, Kory R, Maric, Dragan, Volpe, Giulio, Kouznetsova, Jennifer, Zheng, Wei, Pluchino, Stefano, Hallenbeck, John M
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2015
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759677/
https://ncbi.nlm.nih.gov/pubmed/26661196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X15609939
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker