CMKLR1 deficiency maintains ovarian steroid production in mice treated chronically with dihydrotestosterone

Elevated serum chemerin levels correlate with increased severity of polycystic ovary syndrome (PCOS). However, the role of CMKLR1 signaling in ovarian biology under conditions of excess DHT remains unclear. In this study we compared the effects of continuous 90-day high dose DHT exposure (83.3 □g/da...

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Udgivet i:Sci Rep
Main Authors: Tang, Mi, Huang, Chen, Wang, Yu-Fei, Ren, Pei-Gen, Chen, Li, Xiao, Tian-Xia, Wang, Bao-Bei, Pan, Yan-Fei, Tsang, Benjamin K., Zabel, Brian A, Ma, Bao-Hua, Zhao, Hui-Ying, Zhang, Jian V.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759558/
https://ncbi.nlm.nih.gov/pubmed/26893072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21328
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