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Hydrophobic bile acids relax rat detrusor contraction via inhibiting the opening of the Na(+)/Ca(2+) exchanger

Hydrophobic bile acids (BAs) are thought to inhibit smooth muscle contractility in several organs. The present study was undertaken to investigate the effects of hydrophobic BAs on the detrusor contractility of rat bladder and to explore the possible mechanism. Lithocholic acid (LCA) treatment incre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhu, Jingzhen, Dong, Xingyou, Liu, Qian, Wu, Chao, Wang, Qingqing, Long, Zhou, Li, Longkun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759538/
https://ncbi.nlm.nih.gov/pubmed/26892434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21358
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