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Hydrophobic bile acids relax rat detrusor contraction via inhibiting the opening of the Na(+)/Ca(2+) exchanger

Hydrophobic bile acids (BAs) are thought to inhibit smooth muscle contractility in several organs. The present study was undertaken to investigate the effects of hydrophobic BAs on the detrusor contractility of rat bladder and to explore the possible mechanism. Lithocholic acid (LCA) treatment incre...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Zhu, Jingzhen, Dong, Xingyou, Liu, Qian, Wu, Chao, Wang, Qingqing, Long, Zhou, Li, Longkun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759538/
https://ncbi.nlm.nih.gov/pubmed/26892434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21358
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