Verteporfin inhibits YAP function through up-regulating 14-3-3σ sequestering YAP in the cytoplasm

Yes-associated protein (YAP), the central mediator of Hippo pathway, not only regulates a diversity of cellular processes during development but also plays a pivotal role in tumorigenesis. YAP is overexpressed in many types of human cancers with its expression level being associated with patient out...

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Publicat a:Am J Cancer Res
Autors principals: Wang, Chao, Zhu, Xiaoyong, Feng, Weiwei, Yu, Yinhua, Jeong, Kangjin, Guo, Wei, Lu, Yiling, Mills, Gordon B
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759394/
https://ncbi.nlm.nih.gov/pubmed/27073720
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