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Verteporfin inhibits YAP function through up-regulating 14-3-3σ sequestering YAP in the cytoplasm
Yes-associated protein (YAP), the central mediator of Hippo pathway, not only regulates a diversity of cellular processes during development but also plays a pivotal role in tumorigenesis. YAP is overexpressed in many types of human cancers with its expression level being associated with patient out...
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| Publicado no: | Am J Cancer Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
e-Century Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4759394/ https://ncbi.nlm.nih.gov/pubmed/27073720 |
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