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Filamin A Is Involved in HIV-1 Vpu-mediated Evasion of Host Restriction by Modulating Tetherin Expression

Tetherin, also known as bone marrow stromal antigen 2 (BST-2), inhibits the release of a wide range of enveloped viruses, including human immunodeficiency virus, type 1 (HIV-1) by directly tethering nascent virions to the surface of infected cells. The HIV-1 accessary protein Vpu counteracts tetheri...

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Publicado en:J Biol Chem
Main Authors: Dotson, Dominique, Woodruff, Elvin A., Villalta, Fernando, Dong, Xinhong
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759197/
https://ncbi.nlm.nih.gov/pubmed/26742839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.708123
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