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Identification of calcium-modulating cyclophilin ligand as a human host restriction to HIV-1 release overcome by Vpu
The HIV-1 Vpu protein is required for efficient viral release from human cells. For HIV-2, the envelope (Env) protein replaces the role of Vpu. Both Vpu and HIV-2 Env enhance virus release by counteracting an innate host-cell block within human cells that is absent in African green monkey (AGM) cell...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2652483/ https://ncbi.nlm.nih.gov/pubmed/18500349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1778 |
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