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Cyclic AMP-elevating Agents Promote Cumulus Cell Survival and Hyaluronan Matrix Stability, Thereby Prolonging the Time of Mouse Oocyte Fertilizability

Cumulus cells sustain the development and fertilization of the mammalian oocyte. These cells are retained around the oocyte by a hyaluronan-rich extracellular matrix synthesized before ovulation, a process called cumulus cell-oocyte complex (COC) expansion. Hyaluronan release and dispersion of the c...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Di Giacomo, Monica, Camaioni, Antonella, Klinger, Francesca G., Bonfiglio, Rita, Salustri, Antonietta
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759163/
https://ncbi.nlm.nih.gov/pubmed/26694612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.680983
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