Cyclic AMP-elevating Agents Promote Cumulus Cell Survival and Hyaluronan Matrix Stability, Thereby Prolonging the Time of Mouse Oocyte Fertilizability

Cumulus cells sustain the development and fertilization of the mammalian oocyte. These cells are retained around the oocyte by a hyaluronan-rich extracellular matrix synthesized before ovulation, a process called cumulus cell-oocyte complex (COC) expansion. Hyaluronan release and dispersion of the c...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Di Giacomo, Monica, Camaioni, Antonella, Klinger, Francesca G., Bonfiglio, Rita, Salustri, Antonietta
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759163/
https://ncbi.nlm.nih.gov/pubmed/26694612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.680983
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