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Cyclic AMP-elevating Agents Promote Cumulus Cell Survival and Hyaluronan Matrix Stability, Thereby Prolonging the Time of Mouse Oocyte Fertilizability

Cumulus cells sustain the development and fertilization of the mammalian oocyte. These cells are retained around the oocyte by a hyaluronan-rich extracellular matrix synthesized before ovulation, a process called cumulus cell-oocyte complex (COC) expansion. Hyaluronan release and dispersion of the c...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Di Giacomo, Monica, Camaioni, Antonella, Klinger, Francesca G., Bonfiglio, Rita, Salustri, Antonietta
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759163/
https://ncbi.nlm.nih.gov/pubmed/26694612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.680983
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