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Cyclic AMP-elevating Agents Promote Cumulus Cell Survival and Hyaluronan Matrix Stability, Thereby Prolonging the Time of Mouse Oocyte Fertilizability

Cumulus cells sustain the development and fertilization of the mammalian oocyte. These cells are retained around the oocyte by a hyaluronan-rich extracellular matrix synthesized before ovulation, a process called cumulus cell-oocyte complex (COC) expansion. Hyaluronan release and dispersion of the c...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Di Giacomo, Monica, Camaioni, Antonella, Klinger, Francesca G., Bonfiglio, Rita, Salustri, Antonietta
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759163/
https://ncbi.nlm.nih.gov/pubmed/26694612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.680983
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