A Lipolytic Lecithin:Cholesterol Acyltransferase Secreted by Toxoplasma Facilitates Parasite Replication and Egress

The protozoan parasite Toxoplasma gondii develops within a parasitophorous vacuole (PV) in mammalian cells, where it scavenges cholesterol. When cholesterol is present in excess in its environment, the parasite expulses this lipid into the PV or esterifies it for storage in lipid bodies. Here, we ch...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Pszenny, Viviana, Ehrenman, Karen, Romano, Julia D., Kennard, Andrea, Schultz, Aric, Roos, David S., Grigg, Michael E., Carruthers, Vern B., Coppens, Isabelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759155/
https://ncbi.nlm.nih.gov/pubmed/26694607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.671974
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