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Lecithin:cholesterol acyltransferase: old friend or foe in atherosclerosis?

Lecithin:cholesterol acyltransferase (LCAT) is a key enzyme that catalyzes the esterification of free cholesterol in plasma lipoproteins and plays a critical role in high-density lipoprotein (HDL) metabolism. Deficiency leads to accumulation of nascent preβ-HDL due to impaired maturation of HDL part...

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Detalhes bibliográficos
Main Authors: Kunnen, Sandra, Van Eck, Miranda
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413220/
https://ncbi.nlm.nih.gov/pubmed/22566575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R024513
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