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Lecithin:cholesterol acyltransferase: old friend or foe in atherosclerosis?
Lecithin:cholesterol acyltransferase (LCAT) is a key enzyme that catalyzes the esterification of free cholesterol in plasma lipoproteins and plays a critical role in high-density lipoprotein (HDL) metabolism. Deficiency leads to accumulation of nascent preβ-HDL due to impaired maturation of HDL part...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Biochemistry and Molecular Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413220/ https://ncbi.nlm.nih.gov/pubmed/22566575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R024513 |
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