Angiotensin II stimulates superoxide production by nitric oxide synthase in thick ascending limbs

Angiotensin II (Ang II) causes nitric oxide synthase (NOS) to become a source of superoxide (O(2) (−)) via a protein kinase C (PKC)‐dependent process in endothelial cells. Ang II stimulates both NO and O(2) (−) production in thick ascending limbs. We hypothesized that Ang II causes O(2) (−) producti...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Gonzalez‐Vicente, Agustin, Saikumar, Jagannath H., Massey, Katherine J., Hong, Nancy J., Dominici, Fernando P., Carretero, Oscar A., Garvin, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759044/
https://ncbi.nlm.nih.gov/pubmed/26884476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12697
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