SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids

There are unprecedented epidemics of obesity, such as type II diabetes and non-alcoholic fatty liver diseases (NAFLD) in developed countries. A concerning percentage of American children are being affected by obesity and NAFLD. Studies have suggested that the maternal environment in utero might play...

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Udgivet i:PLoS One
Main Authors: Tobita, Takamasa, Guzman-Lepe, Jorge, Takeishi, Kazuki, Nakao, Toshimasa, Wang, Yang, Meng, Fanying, Deng, Chu-Xia, Collin de l’Hortet, Alexandra, Soto-Gutierrez, Alejandro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758736/
https://ncbi.nlm.nih.gov/pubmed/26890260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149344
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