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Unmasking Heavily O-Glycosylated Serum Proteins Using Perchloric Acid: Identification of Serum Proteoglycan 4 and Protease C1 Inhibitor as Molecular Indicators for Screening of Breast Cancer

Heavily glycosylated mucin glycopeptides such as CA 27.29 and CA 15–3 are currently being used as biomarkers for detection and monitoring of breast cancer. However, they are not well detected at the early stages of the cancer. In the present study, perchloric acid (PCA) was used to enhance detection...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Lee, Cheng-Siang, Taib, Nur Aishah Mohd, Ashrafzadeh, Ali, Fadzli, Farhana, Harun, Faizah, Rahmat, Kartini, Hoong, See Mee, Abdul-Rahman, Puteri Shafinaz, Hashim, Onn Haji
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758733/
https://ncbi.nlm.nih.gov/pubmed/26890881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149551
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