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Unmasking Heavily O-Glycosylated Serum Proteins Using Perchloric Acid: Identification of Serum Proteoglycan 4 and Protease C1 Inhibitor as Molecular Indicators for Screening of Breast Cancer

Heavily glycosylated mucin glycopeptides such as CA 27.29 and CA 15–3 are currently being used as biomarkers for detection and monitoring of breast cancer. However, they are not well detected at the early stages of the cancer. In the present study, perchloric acid (PCA) was used to enhance detection...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Cheng-Siang, Taib, Nur Aishah Mohd, Ashrafzadeh, Ali, Fadzli, Farhana, Harun, Faizah, Rahmat, Kartini, Hoong, See Mee, Abdul-Rahman, Puteri Shafinaz, Hashim, Onn Haji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758733/
https://ncbi.nlm.nih.gov/pubmed/26890881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149551
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