Progression of MRI markers in cerebral small vessel disease: Sample size considerations for clinical trials

Detecting treatment efficacy using cognitive change in trials of cerebral small vessel disease (SVD) has been challenging, making the use of surrogate markers such as magnetic resonance imaging (MRI) attractive. We determined the sensitivity of MRI to change in SVD and used this information to calcu...

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Détails bibliographiques
Publié dans:J Cereb Blood Flow Metab
Auteurs principaux: Benjamin, Philip, Zeestraten, Eva, Lambert, Christian, Chis Ster, Irina, Williams, Owen A, Lawrence, Andrew J, Patel, Bhavini, MacKinnon, Andrew D, Barrick, Thomas R, Markus, Hugh S
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2016
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758545/
https://ncbi.nlm.nih.gov/pubmed/26036939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.113
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