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Progression of MRI markers in cerebral small vessel disease: Sample size considerations for clinical trials

Detecting treatment efficacy using cognitive change in trials of cerebral small vessel disease (SVD) has been challenging, making the use of surrogate markers such as magnetic resonance imaging (MRI) attractive. We determined the sensitivity of MRI to change in SVD and used this information to calcu...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Benjamin, Philip, Zeestraten, Eva, Lambert, Christian, Chis Ster, Irina, Williams, Owen A, Lawrence, Andrew J, Patel, Bhavini, MacKinnon, Andrew D, Barrick, Thomas R, Markus, Hugh S
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758545/
https://ncbi.nlm.nih.gov/pubmed/26036939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.113
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