Inhibitory effects of fasudil on renal interstitial fibrosis induced by unilateral ureteral obstruction

Renal fibrosis is the major cause of chronic kidney disease, and the Rho/Rho-associated coiled-coil kinase (ROCK) signaling cascade is involved in the renal fibrotic processes. Several studies have reported that ROCK inhibitors attenuate renal fibrosis. However, the mechanism of this process remains...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Med Rep
Prif Awduron: BABA, ITSUKO, EGI, YASUHIRO, UTSUMI, HIROYUKI, KAKIMOTO, TETSUHIRO, SUZUKI, KAZUO
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2015
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758322/
https://ncbi.nlm.nih.gov/pubmed/26498136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4467
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