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Inhibitory effects of fasudil on renal interstitial fibrosis induced by unilateral ureteral obstruction

Renal fibrosis is the major cause of chronic kidney disease, and the Rho/Rho-associated coiled-coil kinase (ROCK) signaling cascade is involved in the renal fibrotic processes. Several studies have reported that ROCK inhibitors attenuate renal fibrosis. However, the mechanism of this process remains...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: BABA, ITSUKO, EGI, YASUHIRO, UTSUMI, HIROYUKI, KAKIMOTO, TETSUHIRO, SUZUKI, KAZUO
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758322/
https://ncbi.nlm.nih.gov/pubmed/26498136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4467
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