Novel hydroxybutyl chitosan nanoparticles for siRNA delivery targeting tissue factor inhibits proliferation and induces apoptosis in human vascular smooth muscle cells

Chitosan, a polysaccharide isolated from shrimp and other crustacean shells, has been widely investigated for DNA and siRNA delivery. Despite substantial effort having been made to improve chitosan as a non-viral gene delivery vector, the application is severely limited by its poor solubility under...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: WAN, KANG, LI, JIAN, LI, DAN, GE, JUNHUA, WANG, YUNLONG, LI, XUEXUN, GUO, YONGFANG, GUO, JUNJIE, LENG, MIN, WANG, PAN, AN, YI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758285/
https://ncbi.nlm.nih.gov/pubmed/26497351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4461
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