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Positive and negative selection of the T cell repertoire: what thymocytes see and don't see
The fate of developing T cells is specified by interactions of their antigen receptor with self-peptide/MHC complexes displayed by thymic antigen presenting cells (APCs). Various thymic APCs subsets are strategically positioned in particular thymic microenvironments and orchestrate the selection of...
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| Vydáno v: | Nat Rev Immunol |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4757912/ https://ncbi.nlm.nih.gov/pubmed/24830344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3667 |
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