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Dysfunction of Wntless triggers the retrograde Golgi-to-ER transport of Wingless and induces ER stress

Secreted Wnts play diverse roles in a non-cell-autonomous fashion. However, the cell-autonomous effect of unsecreted Wnts remains unknown. Endoplasmic reticulum (ER) stress is observed in specialized secretory cells and participates in pathophysiological processes. The correlation between Wnt secret...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Peng, Zhou, Lujun, Pei, Chunli, Lin, Xinhua, Yuan, Zengqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757895/
https://ncbi.nlm.nih.gov/pubmed/26887613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19418
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