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Dysfunction of Wntless triggers the retrograde Golgi-to-ER transport of Wingless and induces ER stress
Secreted Wnts play diverse roles in a non-cell-autonomous fashion. However, the cell-autonomous effect of unsecreted Wnts remains unknown. Endoplasmic reticulum (ER) stress is observed in specialized secretory cells and participates in pathophysiological processes. The correlation between Wnt secret...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4757895/ https://ncbi.nlm.nih.gov/pubmed/26887613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19418 |
| Oznake: |
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