An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts

Cancer is a heterogeneous disease caused by diverse genomic alterations in oncogenes and tumor suppressor genes. Despite recent advances in high-throughput sequencing technologies and development of targeted therapies, novel cancer drug development is limited due to the high attrition rate from clin...

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Bibliographic Details
Published in:Mol Cells
Main Authors: Cho, Sung-Yup, Kang, Wonyoung, Han, Jee Yun, Min, Seoyeon, Kang, Jinjoo, Lee, Ahra, Kwon, Jee Young, Lee, Charles, Park, Hansoo
Format: Artigo
Language:Inglês
Published: Korean Society for Molecular and Cellular Biology 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757806/
https://ncbi.nlm.nih.gov/pubmed/26831452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2016.2350
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