Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain

Amphetamines elevate extracellular dopamine, but the underlying mechanisms remain uncertain. Here we show in rodents that acute pharmacological inhibition of the vesicular monoamine transporter (VMAT) blocks amphetamine-induced locomotion and self-administration without impacting cocaine-induced beh...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Freyberg, Zachary, Sonders, Mark S., Aguilar, Jenny I., Hiranita, Takato, Karam, Caline S., Flores, Jorge, Pizzo, Andrea B., Zhang, Yuchao, Farino, Zachary J., Chen, Audrey, Martin, Ciara A., Kopajtic, Theresa A., Fei, Hao, Hu, Gang, Lin, Yi-Ying, Mosharov, Eugene V., McCabe, Brian D., Freyberg, Robin, Wimalasena, Kandatege, Hsin, Ling-Wei, Sames, Dalibor, Krantz, David E., Katz, Jonathan L., Sulzer, David, Javitch, Jonathan A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757768/
https://ncbi.nlm.nih.gov/pubmed/26879809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10652
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