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Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain

Amphetamines elevate extracellular dopamine, but the underlying mechanisms remain uncertain. Here we show in rodents that acute pharmacological inhibition of the vesicular monoamine transporter (VMAT) blocks amphetamine-induced locomotion and self-administration without impacting cocaine-induced beh...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Freyberg, Zachary, Sonders, Mark S., Aguilar, Jenny I., Hiranita, Takato, Karam, Caline S., Flores, Jorge, Pizzo, Andrea B., Zhang, Yuchao, Farino, Zachary J., Chen, Audrey, Martin, Ciara A., Kopajtic, Theresa A., Fei, Hao, Hu, Gang, Lin, Yi-Ying, Mosharov, Eugene V., McCabe, Brian D., Freyberg, Robin, Wimalasena, Kandatege, Hsin, Ling-Wei, Sames, Dalibor, Krantz, David E., Katz, Jonathan L., Sulzer, David, Javitch, Jonathan A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757768/
https://ncbi.nlm.nih.gov/pubmed/26879809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10652
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